Smart Computational Imaging (SCI) Lab


【第二十九期】华沙理工大学Piotr Zdankowski与Wojciech Krauze教授计算成像专场

发表时间:2023-10-17 09:27作者:SCILab来源:SCILab网址:

波兰华沙理工大学微型机械与光子学研究所的研究助理教授Piotr Zdankowski和助理教授Wojciech Krauze受实验室左超教授邀请,将于北京时间10月22日上午9:00-11:15在电子工程与光电技术学院B205为我实验室以及我校OPTICA&SPIE学生分会同学们分别开展两场学术讲座。

报告题目(一):Multidimensional quantitative computational imaging andits applications biomedical imaging

报告人:Piotr Zdankowski


Dr Piotr Zdankowski is from Instituteof Micromechanics and Photonics, Warsaw University of Technology, Warsaw, Poland.He is a researcher at the Quantitative Computational Imaging group. His researchactivities are focused on developing novel instruments of quantitative phaseimaging and super-resolution fluorescent microscopy for biomedicalapplications.


Quantitativephase microscopy (QPM) has recently gained considerable interest because itprovides measurable information about the phase distribution of the objectunder study. Subsequently, optical diffraction tomography has made it possibleto reconstruct and image the three-dimensional refractive index distributionwithin a sample and use it as an endogenous contrast agent. It can be appliedto a variety of technical and biological objects. At the QuantitativeComputational Imaging (QCI) group of the Warsaw University of Technology, wedevelop various instruments for quantitative phase imaging and opticaldiffraction tomography characterized by their simplicity, compactness and robustnumerical methods. We show their applications in live cell imaging and cellmigration characterization, imaging of tissue slices, imaging of neurons andbenchmarking the instruments using samples prepared using two photon polymerizations.


报告题目(二):Advances in optical diffraction tomography of biologicalspecimens

报告人:Wojciech Krauze


Dr Wojciech Krauze is from Institute of Micromechanics andPhotonics, Warsaw University of Technology, Warsaw, Poland. He is part of theBioPhase Imaging Group ( His research activities are focused on 3Dquantitative phase imaging methods for analysis of biological specimens.


Optical diffraction tomography (ODT)is a label-free method converting optical images of transparent samples into 3Drefractive index (RI) distributions, essential for assessing cell cycle stages,biochemical effects, and environmental impacts. Current ODT advances aim toenhance resolution and signal-to-noise ratio in tomographic reconstructions andaddress light scattering in thick biological samples.Two main strategies areemerging. First, multiple-wavelength illumination elevates signal qualitycompared to single-wavelength methods. Second, a "transflective"approach combines transmission and reflection data for improved resolution.However, the quantitative accuracy of these experimental results is oftenoverlooked, typically relying on simulations or measurements of simple objects.A solution involves 3D-printed microphantoms created via two-photonphotopolymerization, providing known geometry, RI, and controllable scattering.These microphantoms facilitate objective assessment and comparison of differentmethods for addressing light scattering challenges in thick biologicalsamples.During my presentation at NJUST, I will summarize recent advances inODT and will discuss the most promising future directions.


图文|王晨阳 侯天语

                               复审| 孙菲 左超


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